Registration Dossier

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
explosiveness, other
Type of information:
other: Expert assessment
Adequacy of study:
key study
Study period:
July 2017, 4
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: This assessment is based on a review of the molecular structure (functionality) within calcium titanium trioxide and relevant REACH and CLP Regulation
Qualifier:
no guideline required
Principles of method if other than guideline:
The purpose of this expert assessment was to determine the explosive potential of calcium titanium trioxide. This was achieved by examining the molecular structure (functionality) of the substance with reference to relevant regulation, namely the Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH) Regulation (EC) No 1907/2006 and the Classification, Labelling, and Packaging (CLP) Regulation (EC) No 1272/2008. Certain groups of elements are commonly associated with explosive behaviour, as described in Table A6.1 of Appendix 6, UN Recommendations on the Transport of Dangerous Goods: Manual of Tests and Criteria, 6th Ed. These structural motifs were subsequently referred to as part of a screening procedure.
GLP compliance:
no
Key result
Test series:
other: Not applicable
Method:
other: Expert assessment
Parameter:
other: Molecular structure (functionality)
Result:
result is considered "-" (negative)
Remarks on result:
other: Calcium titanium trioxide is not considered to have chemical functionality associated with explosive properties
Functional Group (Examples)* Conclusion
C-C Unsaturation (Acetylenes, Acetylides, 1,2-dienes) Not present
C-Metal and N-Metal (Grignard Reagents, Organo-lithium Compounds) Not present
Contiguous N Atoms (Azides, Aliphatic Azo Compounds, Diazonium Salts, Hydrazines Not present
Contiguous O Atoms (Peroxides, Ozonides) Not present
N-O (Hydroxylamines, Nitrates, Nitro Compounds, Nitroso Compounds, N-Oxides) Not present
N-Halogen (Chloramines, Fluoroamines) Not present
O-Halogen (Chlorates, Perchlorates) Not present

*Taken from Table A6.1 in Appendix 6 of the UN RTDG, Manual of Tests and Criteria.

Interpretation of results:
GHS criteria not met
Conclusions:
Following expert assessment, it has been concluded that calcium titanium trioxide does not have explosive properties given a lack of structural features typically associated with explosiveness.
Executive summary:

An assessment was performed to assess calcium titanium trioxide for explosive behaviour, predominantly by reviewing the molecular structure (functionality) of the registered substance and that of titanium dioxide, which is a potential impurity. A screening procedure was undertaken in line with Section 7.11 of the REACH Regulation (EC) No 1907/2006 and Section 2.1.4 of the CLP Regulation (EC) No 1272/2008, as well as in reference to a number of structural motifs associated with explosive properties (Table A6.1 of Appendix 6, UN Recommendations on the Transport of Dangerous Goods: Manual of Tests and Criteria, 6th Ed). Chemical functional groups in Table A6.1 include (but are not limited to) C-C unsaturation (acetylenes, acetylides, 1,2-dienes), C-metal and N-metal (Grignard reagents, organo-lithium compounds), contiguous O atoms (peroxides, ozonides) and N-halogen (chloramines, fluoroamines). It was concluded that calcium titanium trioxide is not explosive as no structural features were identified that are typically associated with explosive behaviour. Subsequently, further study is not required (REACH Regulation (EC) No 1907/2006).

Description of key information

An assessment was performed to assess calcium titanium trioxide for explosive behaviour, predominantly by reviewing the molecular structure (functionality) of the registered substance and that of titanium dioxide, which is a potential impurity. A screening procedure was undertaken in line with Section 7.11 of the REACH Regulation (EC) No 1907/2006 and Section 2.1.4 of the CLP Regulation (EC) No 1272/2008, as well as in reference to a number of structural motifs associated with explosive properties (Table A6.1 of Appendix 6, UN Recommendations on the Transport of Dangerous Goods: Manual of Tests and Criteria, 6th Ed). Chemical functional groups in Table A6.1 include (but are not limited to) C-C unsaturation (acetylenes, acetylides, 1,2-dienes), C-metal and N-metal (Grignard reagents, organo-lithium compounds), contiguous O atoms (peroxides, ozonides) and N-halogen (chloramines, fluoroamines). It was concluded that calcium titanium trioxide is not explosive as no structural features were identified that are typically associated with explosive behaviour. Subsequently, further study is not required (REACH Regulation (EC) No 1907/2006).

Key value for chemical safety assessment

Explosiveness:
non explosive

Additional information

Justification for classification or non-classification