Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: No OECD guideline or GLP defined. Insufficient data documentation.
Data source
Reference
- Reference Type:
- publication
- Title:
- Studies on the toxicity and skin effects of compounds used in the rubber and plastics industries
- Author:
- Mallette F.S., von Haam E.
- Year:
- 1 952
- Bibliographic source:
- Arch. Hyg. Occup. Med. 6, 231-236 (1952)
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- other: human subjects
- Principles of method if other than guideline:
- Sensitization toxicity in human
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Reaction mass of 3-methylphenyl diphenyl phosphate, 4-methylphenyl diphenyl phosphate, bis(3-methylphenyl) phenyl phosphate, 3-methylphenyl 4-methylphenyl phenyl phosphate and triphenyl phosphate
- Molecular formula:
- 3-methylphenyl diphenyl phosphate: C19H17O4P 4-methylphenyl diphenyl phosphate´: C19H17O4P triphenyl phosphate: C18H15O4P bis(3-methylphenyl) phenyl phosphate: C20H19O4P 3-methylphenyl 4-methylphenyl phenyl phosphate: C20H19O4P
- IUPAC Name:
- Reaction mass of 3-methylphenyl diphenyl phosphate, 4-methylphenyl diphenyl phosphate, bis(3-methylphenyl) phenyl phosphate, 3-methylphenyl 4-methylphenyl phenyl phosphate and triphenyl phosphate
- Reference substance name:
- chemical name: Diphenyl tolyl phosphate MCS
- IUPAC Name:
- chemical name: Diphenyl tolyl phosphate MCS
- Details on test material:
- Santicizer 140= monotolyldiphenyl phosphate
Constituent 1
Constituent 2
Method
- Type of population:
- not specified
- Controls:
- no data
- Route of administration:
- dermal
Results and discussion
Any other information on results incl. tables
The test substance was not found to have a sensitizing effect.
Applicant's summary and conclusion
- Executive summary:
In a patch test the test substance was tested in 15 -30 human subjects. Sensitation tests were performed two weeks after the primary irritation test. The test substance was not found to have a sensitizing effect.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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