Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

One GLP compliant study is available for Disflamoll DPK (Weyers, 2006),

the 72-hour ErC50 (growth) was calculated to be 0.55 mg/L. The 72- hour EbC50 (biomass) was calculated to be 0.27 mg/L. Corresponding NOEC values were 0.11 and 0.022 mg/L, respectively. Two other studies have been reported using diphenyl cresyl phosphate as the test material, (Ueda et al, 1991 and Wong and Chau, 1984). The Ueda et al study gave a 72 hour EC50was determined to be 0.99 mg/L and the corresponding NOEC was 0.55 mg/L whilst the Wong and Chau study provided 4 hour medium inhibition concentrations (IC50) values were determined to be 0.7 mg/L for A. falcatus, 1.0 mg/L for S. quadricauda and 0.5 mg/L for Lake Ontario phytoplankton.

Key value for chemical safety assessment

EC50 for freshwater algae:
0.55 mg/L
EC10 or NOEC for freshwater algae:
0.11 mg/L

Additional information

A 72 hour algal inhibition study, according to EU method C.3, with Disflamoll DPK has been reported (Weyers, 2006). The 72-hour ErC50 (growth) was calculated to be 0.55 mg/L. The 72- hour EbC50 (biomass) was calculated to be 0.27 mg/L. Corresponding NOEC values were 0.11 and 0.022 mg/L, respectively.

A 72 hour algal inhibition study, according to OECD 201, was conducted with diphenyl cresyl phosphate (Ueda et al, 1991). The 72 hour EC50was determined to be 0.99 mg/L and the corresponding NOEC was 0.55 mg/L.

Primary productivity of tolyl diphenyl phosphate was measured in a series of non-standard studies with pure algal cultures of Scenedesmus quadricauda and Ankistrodesmus falcatus and natural phtyoplankton from Lake Ontario (Wong and Chau, 1984). The 4 hour medium inhibition concentrations (IC50) values were determined to be 0.7 mg/L for A. falcatus, 1.0 mg/L for S. quadricauda and 0.5 mg/L for Lake Ontario phytoplankton.