Registration Dossier
Registration Dossier
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EC number: 269-144-1 | CAS number: 68188-18-1
Repeated dose toxicity: dermal
Administrative data
- Endpoint:
- short-term repeated dose toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- before July 1975
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Documentation of composition/type of substance is insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 975
- Report date:
- 1975
Materials and methods
- GLP compliance:
- no
Test material
- Reference substance name:
- Paraffin oils, sulfochlorinated, saponified
- EC Number:
- 269-144-1
- EC Name:
- Paraffin oils, sulfochlorinated, saponified
- Cas Number:
- 68188-18-1
- Molecular formula:
- typical example: C15H31Na03S
- IUPAC Name:
- n-C14-C17 alkanes, secondary monosulphonic acids, sodium salts
- Details on test material:
- purity not specified
Constituent 1
- Specific details on test material used for the study:
- Information from study report:
Alkansulfonate, technical product, 93.3 %, white large crystals
Results and discussion
Effect levels
- Dose descriptor:
- NOAEL
- Effect level:
- 2 other: mg/kg bw, substance applied as 0.2% aqueous solution
- Basis for effect level:
- dermal irritation
- other: Basis for effect level: After repeated treatment with 250 mg/kg bw (applied as 25% aqueous solution) oedema, corrosivity and necrosis at site of application was reported. No effects indicating systemic toxicity were reported.
Target system / organ toxicity
- Critical effects observed:
- yes
- Organ:
- skin
Applicant's summary and conclusion
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