Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

The skin sensitisation potential of FR-370 was tested in the albino guinea pig. Maximum concentration not causing irritating effects in  preliminary test: 100 %. Evidence of sensitisation of each challenge concentration: 0%. All animals remained healthy throughout the study. No irritation was noted on any animal at any time during the study. The test material is judged to be non-sensitising when topically applied to Hartley guinea pigs.

Migrated from Short description of key information:
skin sensitization: non-sensitizing

Justification for classification or non-classification

Based on the experimental results and according to the EEC criteria for classification and labelling requirements for dangerous substances and preparations (Guidelines in Commission Directive 93/21/EEC, 27th April 1993), FR-370 does not have to be classified and has no obligatory labelling requirement for sensitisation by skin contact .