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Short-term toxicity to aquatic invertebrates

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Description of key information

PB-370 determination of acute toxicity to daphnia (48 h, static limit test)

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
0.016 mg/L

Additional information

A static acute toxicity with Daphnia magna (n=20) exposed to 100 mg/L FR-370. Measured concentrations of PB-370 at the start of the test was at the approximate value of 12.3 -31.7 ppm. At 48 h PB-370 was either not quantifiable or not detectable. Immobilization among the D. magna exposed to PB-370 for 48 h was 1%. There were no immobilized D. magnain the control group. Based on these results the EC50 for PB-370 is greater than its maximum solubility in water.

Thus, the water solubility value of 0.0156 mg/l was taken for chemical safety assessment.