Registration Dossier

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

PB-370: Chronic life-cycle toxicity to the water flea, daphnia magna under static-renewal conditions

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.016 mg/L

Additional information

After 16-days, mortality ranged from 0 percent at nominal test concentrations of 800 and 3200mg/l to 8 percent at nominal test concentration 400mg/L. No statistical significant increase in mortality was detected as compared to the control. The 16-day EC50 value based on nominal test concentration was > 3200 µg/L.

Reproduction of daphids was determined by number of neonates. No statistical significant decrease in the number of young produced per adult reproductive day was detected as compared to the control. The no-observed effect concentration (NOEC) was 3200 µg/L (nominal concentration), based upon the lack of significant mortality and reproductive differences at this concentration and at lower test concentrations. The LOEC was not determined but was estimated to be > 3200 µg/L (nominal concentration).

The test concentrations in this study were higher than the actual water solubility value (0.0156 mg/l) of the substance, which was taken for chemical safety assessment.