Registration Dossier

Administrative data

Description of key information

Ziram is not a skin irritant but produces severe ocular lesions and produced signs of respiratory irritation during acute inhalation exposure.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Effects on eye irritation: highly irritating

Effects on respiratory irritation: irritating

Justification for classification or non-classification

Based on the respiratory irritation and severe eye irritation, ziram has to be classified:

DSD: Xi, R37-41

CLP: STOT RE 3, H 335; Eye Damage Cat 1, H318