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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
The experimental phase was undertaken between 29.09.1995 and 07.12.1995
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Type:
log Pow
Partition coefficient:
1.65
Temp.:
20 °C
pH:
>= 7.36 - <= 8.56

The recoveries in the range 89.4 - 98.4 % were obtained in the calculatio of the mass balance.

Description of key information

Log Pow = 1.65 at 20 °C and at pH 7.36-8.56 (EU A.8, shake-flask method)

Key value for chemical safety assessment

Log Kow (Log Pow):
1.65
at the temperature of:
20 °C

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