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EC number: 204-340-2 | CAS number: 119-64-2
AVERAGE SCORE - Erythema: 3.11 - Edema: 1.56 - Irritation index: 4.55/8 = moderately irritant REVERSIBILITY: not complete within 14 days
Irritant response data for each animal at each observation time
Score at time point / Reversibility
Max. score: 4
Eschar formation for all animals
Average 24h, 48h, 72h
Not completely reversible
In a primary skin irritation test with three male and three female rabbits tetrahydronaphthalene was applied with occlusive dressing to the shaved back skin at a dose level of 0.5 mL per animal for 4 h. Residual test substance was washed of with warm water. Skin reaction were scored according to OECD criteria at 1h, 24h, 48h, 72h and 6d, 9d, 11d and 14d after application.
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