Registration Dossier

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Über das Schicksal des Tetrahydronaphthalins (Tetralins) im Tierkörper
Author:
Pohl J and Rawicz M
Year:
1919
Bibliographic source:
Hoppe-Seyler's Z. Physiol. Chem. 104, 95-104

Materials and methods

Type of study / information:
Type of experience: Human - Exposure through Food

Test material

Reference
Name:
Unnamed
Type:
Constituent

Method

Details on exposure:
- Test organisms: Humans - Doses: 5 or 7 g (oral)
- Investigations:   Collection of urine, various reactions, isolation and identification of  substances

Results and discussion

Any other information on results incl. tables

Dark green coloured urine is observed.
An unidentified pigment, naphthalene (91-20-3), and  1,2-dihydronaphthalene 

(447-53-0) are formed.

Applicant's summary and conclusion