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Diss Factsheets
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EC number: 231-493-2 | CAS number: 7585-39-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The NOEC for named parameters is 32 mg/L, the LOEC is 100 mg test item/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 100 mg/L
- EC10 or NOEC for freshwater algae:
- 32 mg/L
Additional information
The toxicity of .beta.-Cyclodextrin (100.6% pure HPLC) to Desmodesmus subspicatus was assed in an Algal Growth Inhibition Test according to OECD Guideline 201. This study encompassed 8 treatment groups (7 dose rates of the test item of 100, 32, 10, 3.2, 1.0, 0.32 and 0.1 mg test item/L and a control) with three replicates per test concentration and six replicates for the control. At test start 50 ml Erlenmeyer flasks were inoculated with 5000 algal cells per ml test medium and defined volumes of the algal suspensions were sampled after 24, 48 and 72 hours for determination of cell densities by spectrophotometrical measurement. The analysis of the test item concentration in the test media was done by determination of TOC content as sum parameter since the test item is stable in aqueous solution and not volatile. During the test period test item concentrations were measured in the range from 83 % to 89 % of the nominal values (for the test concentrations of nominal 32 and 100 mg test item/L). Under the test conditions the test item was sufficiently stable during the test period of 72 hours. Therefore, all reported results are related to nominal concentrations of the test item. The 72-hours EC50 value for the growth rate, biomass and yield could not be calculated due to low effects of .beta.-Cyclodextrin and is supposed to be higher than 100 mg test item/L (the highest concentration tested). The NOEC for named parameters is 32 mg/L, the LOEC is 100 mg test item/L showing a reduction in growth rate of 6.8% , a reduction in yield of 28.6% and a reduction of 34.6% in biomass compared to the control group.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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