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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

The mean biodegradation of.beta.-Cyclodextrin was 75% (ThODNH4); the 10 day window criterion was passed.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

.Beta.-cyclodextrin (100.6% pure, HPLC) was assessed for its’ ready biodegradability in a Manometric Respirometry Test according to OECD Guideline 301F over a period of 28 days. Aerobic activated sludge (micro-organisms from a domestic wastewater treatment plant) was sup.Beta.-cyclodextrin plied by the sewage works of,. The biodegradation was followed. by the oxygen uptake of the micro-organisms during exposure. As a reference item sodium benzoate was tested simultaneously under the same conditions as the test item, and functioned as a procedure control. The mean biodegradation of the test item was 75% (ThODNH4) the 10 day window criterion was passed. The reference item sodium benzoate was sufficiently degraded to a mean of 95% after 14 days and to a mean of 105% after 28 days of incubation, thus confirming the suitability of the aerobic activated sludge inoculum used. In the toxicity control containing both, the test item and the reference item sodium benzoate, a mean of 71% biodegradation was noted within 14 days and 81% biodegradation after 28 days of incubation. Thus, the test item can be assumed to be not inhibitory to the aerobic activated sludge microorganisms.