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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

Not biodegradable: 0% biodegradation in 28 days test period (OECD 302C, read across)

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

Since no studies assessing the biodegradability of 5-[C11-12 (branched) alkyl]-2-hydroxybenzaldehyde oxime, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to the structurally related source substance Benzaldehyde, 2-hydroxy-5-nonyl, oxime, branched (CAS 174333-80-3) was conducted. The read across justification document is attached to chapter 13.

The inherent biodegradation study with the source substance was performed according to GLP and OECD guideline 302C using non-adapted activated sludge as inoculum (Seyfried 2007). The biochemical oxygen demand (BOD) of the test substance in the test media was in the normal range found for the inoculum controls. Thus, the test substance was not biodegradable under the test conditions within 28 days.

In addition, several screening tests for Phenol, dodecyl-, branched (CAS 121158-58-5) are available in the respective REACH dossier published in the ECHA database (see table 2). In general, these tests show that Phenol, dodecyl-, branched is not readily biodegradable according to OECD criteria.

Table 2: Biodegradation test results for Phenol, dodecyl-, branched based on data from the respective REACh dossier.

Test

Result

Reliability

Reference

OECD 301B

25% in 28 days (10 mg/L)

6% in 28 days (20 mg/L)

4

(RL2 given in dossier)

http://apps.echa.europa.eu/registered/data/dossiers/DISS-a0013377-90c2-2db6-e044-00144f67d031/AGGR-7c12bdcd-229a-49fc-a23b-257f5998259c_DISS-a0013377-90c2-2db6-e044-00144f67d031.html#AGGR-7c12bdcd-229a-49fc-a23b-257f5998259c

OECD 302D

10% in 56 days (adaption not specified)

4

(RL1 given in dossier)

http://apps.echa.europa.eu/registered/data/dossiers/DISS-a0013377-90c2-2db6-e044-00144f67d031/AGGR-37593b91-acf6-4a5d-acb1-c1debc584f8b_DISS-a0013377-90c2-2db6-e044-00144f67d031.html#AGGR-37593b91-acf6-4a5d-acb1-c1debc584f8b