Registration Dossier
Registration Dossier
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EC number: 944-572-8 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (3h) > 1000 mg/L, EC10 (3h) = 200.4 mg/L (nominal) for activated sludge (OECD 209, read across)
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 200.4 mg/L
Additional information
Since no studies assessing the short-term toxicity of 5-[C11-12 (branched) alkyl]-2-hydroxybenzaldehyde oxime to aquatic invertebrates is available, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to the structurally related source substance Benzaldehyde, 2-hydroxy-5-nonyl, oxime, branched (CAS 174333-80-3) was conducted. The analogue justification document is attached to chapter 13.
The study with the read across substance was performed according to OECD guideline 209 under GLP conditions using domestic activated sludge as inocculum (Wehrhahn 2010). The test material was applied directly to the test vessels. Analytical monitoring was not performed. All validity criteria were fulfilled. The EC50 is determined to be > 1000 mg/L, while the respective EC10 is determined to be 200.4 mg/L based on nominal concentrations. Based on the high structural similarity which leads to similar behavior in the environment (see analogue justification document) this conclusion can also be considered true for
5-[C11-12 (branched) alkyl]-2-hydroxybenzaldehyde oxime.
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