Registration Dossier
Registration Dossier
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EC number: 403-700-8 | CAS number: 2687-94-7 NOP; SURFADONE LP-100 SURFACTANT
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
Two acute studies are available in birds:
In the key study (Wildlife International Ltd. 1991) the substance was administered by diet for 5 days and gave a LC50 >5620 mg/kg food.
In the supporting study (Wildlife International Ltd. 1991) a single oral gavage dose was administered and gave an LC50 of 1838 mg/kg/bw.
Furthermore, chronic toxicity studies are not indicated in regard to the large dataset for mamamlian data.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for birds:
- 5 620 mg/kg food
Additional information
Two acute studies are available in birds.
In the key study (Wildlife International Ltd. 1991) the substance was administered by diet for 5 days and gave a LC50 >5620 mg/kg food. In the supporting study (Wildlife International Ltd. 1991) a single oral gavage dose was administered and gave an LC50 of 1838 mg/kg/bw.
According to Regulation (EC) 1907/2006, Annex X Column 2, chronic avian testing is not needed due to the large mamallian dataset available on N-(n-octyl)-2-pyrrolidinone.
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