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Toxicity to soil macroorganisms except arthropods

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toxicity to soil macroorganisms except arthropods: long-term
Data waiving:
other justification
Justification for data waiving:
the study does not need to be conducted because direct and indirect exposure of the soil compartment is unlikely

Table 1: Mackay Level I calculation (BASF, 2008)


Percent distribution in media (%)









Susp. sediment







Description of key information

Exposure of the test item to soil organism is very unlikely.

Key value for chemical safety assessment

Additional information

The test item is highly soluble in water (~550 g/L, c.f. 4.8.) and is readily biodegradable (Frauenhofer IME, 2011) therefore an exposure via soil is not expected. In accordance with Annex IX of Regulation (EC) No 1907/2006, testing is not required as the substance is not persistent in this compartment, due to physico-chemical properties and the proven ready biodegradability. This is underlined by valid Mackay Level I distribution modelling (BASF, 2008). According to this calculation soil is not a target compartment of the test item. When released into the environment 98.8 % will remain in the water phase and 1,16 % will evaporate to the air (see table 1). In order to this, a distribution to soil and sediment is not expected. In addition, the test item has a low log Kow (0.35, Hansch et al., 1995) and does not tend to bioaccumulate in organisms. In conclusion, exposure of soil organisms is very unlikely.

An experimental study similar to OECD guideline 207 with Eisenia fetida is available (Roberts, 1984). The test organisms were exposed to the test item via filter paper for 48 h and the LC50 was determined. Several substances were tested in this publication; therefore, the effect values were reported in categories instead of single values. The test item was categorized to be extremely toxic towards Eisenia fetida with an LC50 value between 1 and 10 µg/cm². No long-term data are available.

Although an effect of the test item on soil macroorganisms was determined an exposure of these organisms is very unlikely under environmental conditions. In the present experimental set-up, the test organisms were exposed via filter paper which does not adequately reflect real exposure via the soil. Based on this,  the toxicity of the test item to soil macroorganisms is probably overestimated by using the experimental data from the publication.