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EC number: 200-001-8 | CAS number: 50-00-0
Mortality rates in male Wistar rats after oral application of formaldehyde
Dose in mg/kg bw
The study is comparable to OECD 401 with accepatable restrictions (symptoms not described; no necropsy; purity of test substance not given).
Male Wistar rats (n= 6 -16) were gavaged with formalin or paraformaldehyde solution in water at concentrations of 2 or 4 %. The range of LD50 values was between 460 and 830 mg/kg bw. There is no significant difference between the paraformaldehyde and the formalin solution, nor any significant difference concerning the concentration (2 or 4% solutions). The mean oral LD50 value of five independent experiments in male Wistar rats is 640 mg/kg bw.
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