Registration Dossier

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Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

Two studies on skin sensitisation are available for maleic acid. Maleic acid was sensitising in a guinea pig maximisation test as well as in a local lymph node assay.

Migrated from Short description of key information:
Weber 2004, LLNA, OECD 429: sensitising
Weiss 2002, GPMT, OECD 406: sensitising

Justification for classification or non-classification

According to the results of the studies available maleic acid has to be classified as "R43 May cause sensitisation by skin contact" / "Skin sensitisation Category 1".