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EC number: 203-742-5 | CAS number: 110-16-7
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Indrani 2010. Daphnia magna, acute immobilisation test, OECD 202: EC50(48h) = 42.81 mg/L based on measured concentrations
Knie 1983. Short-term toxicity to Daphnia Magna, DIN 38 412 Teil 11: EC50 24h = 160 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 42.81 mg/L
Additional information
In the key study the EC50value for Maleic acid at 48 hours was 42.81 mg/L based on nominal concentrations with fiducial limits at 95% being 33.51 and 54.68 mg/L.
On the basis of the observations made during this test, the NOEC (which is the highest tested concentration of test item at which no effects on Daphnia were observed = No Observed Effect Concentration) was 17.5 mg/L and LOEC (Lowest Observed Effect Concentration) was 30.63 mg/L.
In the repeat definitive test, Daphnia magna were exposed to a concentration of 93.80 mg/L (pH adjusted to 6 to 9). The results of the repeat definitive test have shown 55% immobilisation of daphnids compared to initial definitive test wherein 100% immobilisation was observed at the end of test. Acidic conditions, to an extent, would have played a role in higher immobilization.
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