Registration Dossier

Administrative data

Endpoint:
toxicity to other aquatic vertebrates
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: No guideline study, insufficient documentation on physicochemistry or applied test method. No statistics were reported

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1978

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
other: Spongilla lacustris
Details on test organisms:
gemmules form branches of the freshwater sponge; gemmules were dissected, washed at 4°C and incubated at 15°C

Study design

Test type:
not specified
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h

Test conditions

Test temperature:
15 ± 1°C
Nominal and measured concentrations:
2 test concentrations: 0.1 and 1 mM
Details on test conditions:
distilled and purified freshwater
Reference substance (positive control):
not specified

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
LOEC
Effect conc.:
< 137 327 µg/L
Nominal / measured:
nominal
Conc. based on:
element
Remarks:
fraction total assumed
Basis for effect:
other: germination
Remarks on result:
other: nr
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
13 733 µg/L
Nominal / measured:
nominal
Conc. based on:
element
Remarks:
fraction total assumed
Basis for effect:
other: hatching
Remarks on result:
other: nr
Duration:
72 h
Dose descriptor:
LOEC
Effect conc.:
137 327 µg/L
Nominal / measured:
nominal
Conc. based on:
element
Remarks:
fraction total assumed
Basis for effect:
other: hatching
Remarks on result:
other: nr
Reported statistics and error estimates:
not reported

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
This study followed no guidelines. It contains insufficient documentation on physico-chemical parameters and test methods. the results contain no statistics.