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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The 96-h LC50 is 580 mg/l in the freshwater fish Onchorhynchus mykiss. For marine fish the 96-h LC50 is 574 mg/l for MTBE found in Menidia beryllina; a safety factor of 10 will be applied on this value.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
580 mg/L

Marine water fish

Marine water fish
Effect concentration:
57.4 mg/L

Additional information

There are three guideline studies available for freshwater fish. The studies are either semi-static or flow-through. The most critical study is therefore chosen as the key study. The lowest observed effect concentration is a 96-h LC50 value of 580 mg/l in Onchorhynchus mykiss (Springborn Laboratories Inc., 1994a). As no data is available for marine fish, the data from MTBE are used for read-across. The lowest effect concentration in marine fish for MTBE is a 96 -h LC50 of 574 mg/l in inland silverside (Menidia beryllina) (BenKinney et al., 1994). Applying a safety factor of 10 to this value results in an effect concentration of 57.4 mg/l for TAME. Both values will be used in the assessment.