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TAME is a colourless liquid with a sweetish odor. It has a melting point of < -20 ˚C (Harlan Laboratories, Ltd., 2009a) and a boiling point of 87.3 ºC (Hellenic Petroleum S.A., 2009). The relative density of TAME is 0.77 at 15 ˚C (Huttunen, 1996; Huttunen et al., 1997). The vapour pressure of TAME is 9100 Pa at 25 °C (Harlan Laboratories Ltd, 2009b). The water solubility of TAME is 10400 mg/l at 20 ˚C (Oil Products Research, 1997).The octanol/water partition coefficient (log Pow) is 1.55 (Huttunen, 1996; Huttunen et al., 1997). The substance is not surface active; the surface tension of 1080 mg/l solution in water is 71.3 mN/m at 23.5 °C (SafePharm Laboratories, Ltd., 2008). TAME has a static viscosity of 0.6 mm²/s at 20.5 °C and 0.494 mm²/s at 40.5 °C (SafePharm Laboratories, Ltd., 2008).

The substance has a flash point of -18 °C (PTB Laboratorium 3.43, 2007). Based on this value and a boiling point of 86.3 °C, TAME should be classified as highly flammable (F, R11) / Flammable Liquid Cat. 2 (H225). The molecular structure of TAME does not contain groups that indicate potential reactivity with water or pyrophoric properties. The auto-ignition temperature of TAME is 430°C (Huttunen, 1996; Huttunen et al., 1997). The substance is not expected to have explosive and oxidising properties.

The substance remains undissociated in water, as it does not contain chemical groups which can undergo dissociation. TAME is a stable chemical and is not expected to show instability when mixed with typical organic solvents.

In accordance with column 2 of REACH Annex VII, a study on granulometry is not needed as TAME is a liquid and used in a non solid or granular form.