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Toxicological information

Repeated dose toxicity: inhalation

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Administrative data

Endpoint:
short-term repeated dose toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP, only four test animals.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1970

Materials and methods

Principles of method if other than guideline:
Method: no data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Dodecyl methacrylate
EC Number:
205-570-6
EC Name:
Dodecyl methacrylate
Cas Number:
142-90-5
Molecular formula:
C16H30O2
IUPAC Name:
dodecyl 2-methylprop-2-enoate
Test material form:
liquid

Test animals

Species:
rat
Strain:
not specified
Sex:
male/female

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Duration of treatment / exposure:
4 weeks
Frequency of treatment:
20 x 6 h/d; 5 d/w
Doses / concentrations
Remarks:
Doses / Concentrations:
saturated atmosphere
Basis:

Control animals:
no

Results and discussion

Results of examinations

Clinical signs:
no effects observed

Effect levels

Dose descriptor:
conc. level: saturated atmosphere
Sex:
male/female
Basis for effect level:
other: no toxic signs
Remarks on result:
not measured/tested
Remarks:
Effect level not specified.

Target system / organ toxicity

Critical effects observed:
not specified

Any other information on results incl. tables

No toxic signs: autopsy, organs normal

Applicant's summary and conclusion

Conclusions:
After repeated inhalative screening exposure (20 x 6 h/d; 5 d/w) to 2 female and 2 male rats there were no toxic signs, autopsy and organs normal.
Executive summary:

After repeated inhalative screening exposure (20 x 6 h/d; 5 d/w) to 2 female and 2 male rats there were no toxic signs, autopsy and organs normal.