Dodecyl methacrylate

Acute Toxicity: other routes

Administrative data

Endpoint:

acute toxicity: other routes

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference

Reference Type:

publication

Title:

De la toxicité de quelques esters|acryliques et méthacryliques de l'acrylamide et des polyacrylamides.

Author:

Paulet G, Vidal M

Year:

1975

Bibliographic source:

Arch. Mal. Prof. Med. Trav. Sec. Soc. 36 (1-2): 58-60 [in French, no English abstract]

Materials and methods

Principles of method if other than guideline:

other: no data

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Dodecyl methacrylate

EC Number:

205-570-6

EC Name:

Dodecyl methacrylate

Cas Number:

142-90-5

Molecular formula:

C16H30O2

IUPAC Name:

dodecyl 2-methylprop-2-enoate

Details on test material:

2-Propenoic acid, 2-methyl-, dodecyl ester purity not specified, but commercial grade assumed.

Specific details on test material used for the study:

2-Propenoic acid, 2-methyl dodecylester (CAS: 142-90-5)

Test animals

Species:

rat

Administration / exposure

Route of administration:

intraperitoneal

Results and discussion

Effect levels

Dose descriptor:

LD50

Effect level:

12 000 mg/kg bw

Applicant's summary and conclusion

Conclusions:

In a intraperitoneal acute toxicity study on Dodecyl methacrylate with rats, an LD50: 12 g/kg was observed.

Executive summary:

In a intraperitoneal acute toxicity study on Dodecyl methacrylate with rats, an LD50: 12 g/kg was observed.