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EC number: 921-024-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Oral LD50 (rat) > 5840 mg/kg bw
Dermal LD 50 (rat) > 2920 mg/kg bw
Inhalative LD50 (rat) > 25200 mg/m³
Key value for chemical safety assessment
Additional information
Oral
There are no data available on the acute oral toxicity of hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane. However, there are reliable data available for another category member. Thus, read-across was conducted based on a category-approach.
The acute oral toxicity of hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics was tested following a standard method. Two male and two female rats were exposed to 1, 2, 4, or 8 mL/kg of undiluted test substance orally by gavage. The animals were then observed for the next 9 days for mortality. No animals of either sex died during the study. The LD50was > 8 mL/kg for both male and female rats. Based on the density given in the study report, the LD50was calculated to be higher than approx. 5840 mg/kg bw (Shell Chemicals, 1977).
Inhalation
The acute toxicity of hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane, upon inhalation was tested in rats exposed to 25200 mg/m³ for 4 h. There were no deaths during the study. Besides restless behaviour, increase in respiration rate during the first 15 minutes, partial closing of the eyes and slightly reduced food consumption on day 1 post-exposure, no signs of toxicity were observed. The LC50value was therefore greater than 25200 mg/m³ air (Shell Chemicals, 1988).
Dermal
There are no data available on the acute dermal toxicity of hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane. However, there are reliable data available for another category member. Thus, read-across was conducted based on a category-approach.
Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics were applied on the shaved backs of Charles River CD rats (2/sex/dose) at 1, 2, and 4 mL/kg bw (730, 1460, and 2920 mg/kg bw) for 24 hours in accordance with the method of Noakes and Sanderson, 1969 [Br. J Indust. Med 26:59-64] (similar to OECD 402). No deaths or clinical signs were observed. The LD50was greater than 4 mL/kg bw, corresponding to 2920 mg/kg bw (Shell Chemicals, 1977).Justification for classification or non-classification
The available data on the acute toxicity of hydrocarbons, C6 -C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane as well as structurally related substances are conclusive but not sufficient for classification. However, acute exposure may result in non-lethal narcotic effects and hydrocarbons pose aspiration hazard.
DSD: R65-67
CLP: Aspiration Toxicity Category 1, STOT Single Exposure Category 3 (narcosis)
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