Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

Currently viewing:

Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB

Assessment of PBT/vPvB Properties

PBT/vPvB screening criteria have been used to assess whether the substance may potentially fulfil the PBT or vPvB criteria.

   Persistence Assessment

Tetrahydro-2-methylfuran is not readily biodegradable and the chemical structure of is not suggestive of a hydrolytic degradation mechanism. Therefore, the criteria for P/vP may be met.

Bioaccumulation Assessment

Tetrahydro-2-methylfuran has low potential for bioaccumulation so the criteria for bioaccumulation are not met. The substance is not B or vB.

 Toxicity Assessment


The available short term studies in fish, invertebrates and algae resulted in reliable E(L)C50 values of =100 mg/l. No effects were seen in a reliable long-term limit test in invertebrates (Daphnia magna) resulting in NOECrepro=120 mg/l (measured, arithmetic mean) and the algal NOECgrowth rateis =104 mg/l (measured, geometric mean) in a reliable study. Therefore the criteria for Toxicity based on aquatic ecotoxicity (NOEC <0.01 mg/l) are not met.


The available data indicate that the substance is not classified for specific target organ toxicity, carcinogenicity, mutagenicity or reproductive and developmental toxicity in mammals (See Section 5.9). The criteria for T based on mammalian effects are therefore not met


PBT/vPvB criteria and justification

The registered substance may meet the criteria for P/vP, but does not meet the criteria for B, vB or T. Therefore, the substance is not PBT or vPvB.

 Summary and overall conclusions on PBT or vPvB properties

Overall conclusion:

The substance does not meet the criteria for PBT/vPvB.