Registration Dossier
Registration Dossier
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EC number: 200-554-5 | CAS number: 63-05-8
Endpoint summary
Administrative data
Description of key information
Acute toxicity to fish: After 96 h a LC50 of 8.6 mg/L was determined for Androstendion towards fish. The result is expressed in terms of geometric mean measured concentrations.
Acute toxicity to daphnia: After 48 h an EC50 of 21.4 mg/L was measured. The NOEC for 48 h was 1.0 mg/L, the LOEC was 2.3 mg/L. The results are relating to measured concentrations (measured by TOC).
Toxicity to freshwater algae: The 72 h-EC50 for growth rate reduction based on TWA concentrations was 25 mg/L (95 % confidence interval 18 to 33 mg/L). The NOEC for growth rate reduction equalled a TWA concentration of 2.5 mg/L.
Toxicity to microorganisms: Up to a saturated solution, there was no effect on growth of Pseudomona putida. Therefore, the 16 h-EC10 was determined to be higher than a saturated solution (49.5 mg/L).
All toxicity studies mentioned above are classified as acceptable and satisfy the guideline requirements for the toxicity studies on acute toxicity to aquatic organisms.
Additional information
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