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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
2.7
Temp.:
25 °C
pH:
7
Conclusions:
The partition coefficient (log Pow) of the substance is 2.7 at 25°C and pH 7.
Executive summary:

The n-octanol/water partition coefficient of the test item was determined at 25 °C following OECD Testing Guideline 117 (HPLC method) to be 2.7 at 25 °C and pH 7. This method is based on the correlation of the reversed phase retention data of the test compound with those of reference compounds with known log Pow values.

Description of key information

The partition coefficient (log Pow) of Androst-4-ene-3, 17-dione is 2.7 at 25°C and pH 7.

Key value for chemical safety assessment

Log Kow (Log Pow):
2.7
at the temperature of:
25 °C

Additional information