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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
not specified
GLP compliance:
yes
Type of method:
flask method
Water solubility:
66 mg/L
Temp.:
20 °C
pH:
6.5
Remarks on result:
other: There is no change in the solid state form of the insoluble residue with respect to that one of the starting material.
Conclusions:
Androst-4-ene-3,17-dione can be considered as slightly soluble with a water solubility of 66 mg/L at 20 °C. The mean pH value of the saturated water solutions was determined to be 6.5.
Executive summary:

The water solubility of the substance was determined to be 66 mg/L at 20°C and pH 6.5 according to the EU method A.6 with 95% confidence interval.

Description of key information

Androst-4-ene-3,17-dione can be considered as slightly soluble with a water solubility of 66 mg/L at 20 °C. The mean pH value of the saturated water solutions was determined to be 6.5.

Key value for chemical safety assessment

Water solubility:
66 mg/L
at the temperature of:
20 °C

Additional information