Registration Dossier

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

In a well conducted and reliable test with Daphnia magna (OECD 202) the EC50 (48 h) was 2.18 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
2.18 mg/L

Additional information

In the acute immobilization test with Daphnia magna (STRAUS) the effects of the submission substance was determined according to OECD 202 (2004) under GLP conditions (RL 1). The study was conducted under static conditions over a period of 48 h with 5 nominal test item concentrations ranging from 1.25 to 20.0 mg/L. The test concentrations were verified by analytically. The validity criteria of the test guideline were fulfilled.

Based on the nominal concentrations of the test item the 48 -h EC50 for Daphnia magna was estimated to be 2.18 mg/L (95 % confidence limits: 1.92 - 2.47 mg/L).

In two further toxicity tests with Daphnia magna reported in the EU Risk Assessment Report, EC 50 (48 h) values of 6.8 mg/L and 22.5 mg/L were obtained, respectively.