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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
Publication date: 2002
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature (review)

Data source

Reference
Reference Type:
review article or handbook
Title:
European Union Risk Assessment Report - o-Anisidin
Author:
European Chemicals Bureau
Year:
2002
Bibliographic source:
European Commission, Joint Research Center, EUR 19834 EN, 2nd Priority list, Volume 15

Materials and methods

Principles of method if other than guideline:
Chronic toxicity test on Daphnia magna reproduction
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
o-anisidine
EC Number:
201-963-1
EC Name:
o-anisidine
Cas Number:
90-04-0
Molecular formula:
C7H9NO
IUPAC Name:
2-methoxyaniline
Details on test material:
Commercially available o-anisidine with a purity >= 99%

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
flow-through
Water media type:
freshwater
Limit test:
no
Total exposure duration:
21 d

Results and discussion

Effect concentrationsopen allclose all
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
> 0.206 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
reproduction
Remarks on result:
other: flow-through
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.055 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
reproduction
Remarks on result:
other: flow-through

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
In a chronic toxicity test on Daphnia magna (reproduction) the following effect concentrations of the submission substance were determined:
EC50 (21d, reproduction rate): >0.206 mg/L
NOEC (21d, reproduction rate): 0.0549 mg/L
Executive summary:

In a chronic toxicity test on Daphnia magna (reproduction) reported in the EU Risk Assessment Report the following effect concentrations of the submission substance were determined:

EC50 (21d, reproduction rate): >0.206 mg/L

NOEC (21d, reproduction rate): 0.0549 mg/L