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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
Publication date: 2002
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature (review)

Data source

Reference
Reference Type:
review article or handbook
Title:
European Union Risk Assessment Report - o-Anisidin
Author:
European Chemicals Bureau
Year:
2002
Bibliographic source:
European Commission, Joint Research Center, EUR 19834 EN, 2nd Priority list, Volume 15

Materials and methods

Principles of method if other than guideline:
Chronic toxicity test on Daphnia magna reproduction
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
o-anisidine
EC Number:
201-963-1
EC Name:
o-anisidine
Cas Number:
90-04-0
Molecular formula:
C7H9NO
IUPAC Name:
2-methoxyaniline
Details on test material:
Commercially available o-anisidine with a purity >= 99%

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
flow-through
Water media type:
freshwater
Limit test:
no
Total exposure duration:
21 d

Results and discussion

Effect concentrationsopen allclose all
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
> 0.206 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
reproduction
Remarks on result:
other: flow-through
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.055 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
reproduction
Remarks on result:
other: flow-through

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
In a chronic toxicity test on Daphnia magna (reproduction) the following effect concentrations of the submission substance were determined:
EC50 (21d, reproduction rate): >0.206 mg/L
NOEC (21d, reproduction rate): 0.0549 mg/L
Executive summary:

In a chronic toxicity test on Daphnia magna (reproduction) reported in the EU Risk Assessment Report the following effect concentrations of the submission substance were determined:

EC50 (21d, reproduction rate): >0.206 mg/L

NOEC (21d, reproduction rate): 0.0549 mg/L

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