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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1984
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Insufficient documentation, no analytical verification of the test substance concentration and no data on dissolved oxygen concentration.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1984
Report date:
1984

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
o-anisidine
EC Number:
201-963-1
EC Name:
o-anisidine
Cas Number:
90-04-0
Molecular formula:
C7H9NO
IUPAC Name:
2-methoxyaniline
Details on test material:
Echtrot BB Base flüssig

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 60 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
100 mg/L test item used, containing 60% of submission substance
Basis for effect:
mortality (fish)

Any other information on results incl. tables

Sublethal observations / clinical signs:

No letality observed; after 24 hours at 100 mg/L (60 mg/L submission substance) one fish showed elevated movement of gills and tail-heavy swimming behaviour. The other fish were without symptoms.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
An acute toxicity test on fish (Brachydanio rerio) equivalent or similar to OECD 203 with the test item had the following result:
LC50 (48 and 96 h) > 60 mg/L
Executive summary:

An acute toxicity test on fish (Brachydanio rerio) equivalent or similar to OECD 203 with the test item had the following result:

LC50 (48 and 96 h) > 60 mg/L (100 mg/L test item corresponding to 60 mg/L submission substance).

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