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EC number: 248-258-5 | CAS number: 27138-31-4
A study was performed to assess the eye irritation potential of DPGDB to the rabbit. The study was conducted in accordance with OECD, EC, US EPA and Japanese test guidelines, and in compliance with GLP.
Approximately 0.1 mL of the test substance was instilled into one eye of 6 rabbits, and the effects observed for 72 hours. The eyes were not rinsed after instillation of the test material.
Transient hyperaemia of blood vessels only was observed in all animals. These reactions had resolved in all instances by one or two days after instillation. No corneal damage or iridial inflammation was observed.
There were no signs of toxicity or ill health in any of the rabbits during the observation period.
Instillation of DPGDB into the rabbit eye did not elicit a positive response according to the established test criteria.
DPGDB is not irritant to the eye.
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