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EC number: 248-258-5
CAS number: 27138-31-4
A study was performed
to assess the acute dermal toxicity of the test material DPGDB when
administered to rats. The
study was conducted according to OECD, EC, US EPA, and Japanese (MITI)
test guidelines, and in compliance with GLP.
Ten rats (five males
and five females) were exposed to a single 2000 mg/kg dose of DPGDB by
the dermal route for 24 hours, then observed for 14 days following test
No rats died during the
observation period and no clinical or pathological signs were observed.
No dermal response to treatment was observed in any animal. No
abnormalities were observed during macroscopic examination at study
The acute lethal dermal
dose to rats of DPGDB was demonstrated to be greater than 2000 mg/kg
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