Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Data waiving:
study technically not feasible
Justification for data waiving:
other:

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Diisobutylaluminium hydride
EC Number:
214-729-9
EC Name:
Diisobutylaluminium hydride
Cas Number:
1191-15-7
Molecular formula:
C8H19Al
IUPAC Name:
bis(2-methylpropyl)alumane

Results and discussion

Applicant's summary and conclusion

Conclusions:
Corrosive. Flammable in air at room temperature. Violent reaction with water. Corrosive. Exposure of mammalian species to aluminum alkyls would not generate meaningful data, and no acute oral toxicity studies are required for this substance.
Executive summary:

Corrosive. Flammable in air at room temperature.Violent reaction with water. Corrosive. Short chain aluminum alkyls ignite spontaneously on contact with air and therefore are classified pyrophoric. Reactions of aluminum alkyls with liquids are in some cases explosion like. Exposure of mammalian species to aluminum alkyls would not generate meaningful data, and no acute oral toxicity studies are required for this substance.