Registration Dossier
Registration Dossier
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EC number: 200-756-3 | CAS number: 71-55-6
Toxicity to reproduction
Administrative data
- Endpoint:
- two-generation reproductive toxicity
- Remarks:
- based on test type (migrated information)
- Adequacy of study:
- other information
Data source
Reference
- Title:
- No information
- Author:
- HSDB online via STN
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1,1,1-trichloroethane
- EC Number:
- 200-756-3
- EC Name:
- 1,1,1-trichloroethane
- Cas Number:
- 71-55-6
- Molecular formula:
- C2H3Cl3
- IUPAC Name:
- 1,1,1-trichloroethane
- Details on test material:
- IUCLID4 Test substance: as prescribed by 1.1 - 1.4
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- Swiss
- Sex:
- male/female
Administration / exposure
Doses / concentrations
- Remarks:
- Doses / Concentrations:
0, 0.58, 1.75, or 5.83 mg/l = 0, 100, 300 or 1000 mg/kg
Basis:
Results and discussion
Overall reproductive toxicity
- Reproductive effects observed:
- not specified
Any other information on results incl. tables
RS-Freetext:
No taste aversion evident. There appeared to be no
dose-dependent effects on fertility, gestation, viability or
lactation indices. Pup survival and weight gain were not
adversely affected. No significant lethal mutations or
teratogenic effects in either of the 2 generations tested.
Applicant's summary and conclusion
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