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REACH

1,1,1-trichloroethane

EC number: 200-756-3 | CAS number: 71-55-6

Life Cycle description
Uses advised against

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The results of a number of studies are included in this section together with one comprehensive review.  The study chosen for both freshwater and marine invertebrates were conducted in a closed system to reduce active ingredient losses by volatilisation. The best study on fresh water invertebrates for which a robust study is available is that by Abernethy et al 1986. However, the risk assessment conducted by  De Rooij et al 2004 based on the EuroChlor review contains a better study Bobra et al 1984 which achieved a higher classification for reliability than the  study included in the dossier. As this study has a lower LC50 value for freshwater invertebrates it is used as the endpoint. (as a matter of interest the Abernethy 1986 study restates the results from the Bobra 1983 study but calculates the LC50 incorrectly therefore the two studiesare in fact identical). For marine invertebrates the LC50 value is obtained in a similar way from the EuroChlor review.

Key value for chemical safety assessment

Fresh water invertebrates

Effect concentration:: 57.6 mg/L

Marine water invertebrates

Effect concentration:: 7.5 mg/L

Additional information

The results of the risk assessment De Rooij et al 2004 on theEuro Chlor review of studies available on a freshwater and marine invertebrates are shown below.

Acute studies on freshwater invertebrates

Species	Duration	Study type	Endpoint	Conc. (mg/L)	SF 1000 (ug/L)	Validity	Comments	Reference
Daphnia magna	48h	S,A,C	LC50	57.6	57.6	1		Bobra et al 1984
	48h	S,N,C	LC50	59.6	59.6	2	immobility	Abernethy et al 1986
	48h	S,N,C	LC50	>530	>530	2	NOEC 530mg/L	LeBlanc 1980
	24h	S,N	EC50	2400	2400	3	immobility	Bringmann & Kuhn 1982

Acute studies on marine invertebrates

Species	Duration	Study type	Endpoint	Conc. (mg/L)	SF 1000 (ug/L)	Validity	Comments	Reference
Elminius modestus	48h	S,N,C	LC50	7.5	7.5	2		Pearson & McConnel 1975
Artemia salina	24h	S,N	EC50* 24 48 72	113 44 8	113 44 8	2 (3) (3)	Lack of control data	Sanchez-Fortun et al 1997
Mysidopsis bahia	96h	S,N	LC50	31.2	31.2	4		US EPA 1980

A.salina – three stages tested (24, 48, 72h.

Key: Analysis A = Yes, N = nominal concentration. Study type S = static, SS = semi-static, FT = flow through. C = closed system.

Rating for validity 1 = valid without restriction, 2 = valid with restrictions, 3 = invalid, 4 = not assignable (inadequate data).

See also Overall Remarks in EuroChlor 1999 endpoint study report.

Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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