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EC number: 204-004-5 | CAS number: 112-76-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish
No data on the toxicity of stearoyl chloride is available. There is a fish study available for palmitoyl chloride (BASF AG, 1998).
Palmitoyl chloride hydrolyses rapidly in water therefore fish are mainly exposed to its hydrolysis product, palmitic acid. Test concentrations were clearly above the solubility limit of palmitoyl chloride and palmitic acid as unsoluble test material was visible and the test solutions were cloudy. Test concentrations were analytically verified. No toxic effects within the range of water solubility were observed. The LC50 was determined to be ca. 115 mg/L (BASF, 1998).
With high probability, palmitoyl choride is acutely not harmful to fish.A semi-static test was performed with sodium stearate (CAS 822 -16 -2; Onitsuka et al., 1989). The LC50 was determined to be 125 mg/L.
A limit test was performed with the hydrolysis product stearic acid (Leach, 1977). After 96-h no toxic effect was observed at the tested concentration of 12 mg/L, which is clearly above the limit of water solubility.
The hydrolysis product hydrochloric acid (HCl) was tested in a semi-static acute toxicity test according to OECD 203 withCyprinus carpio. The 96 -h LC50 was 4.92 mg/L (acid equivalent to pH 4.3; OECD 2002). The hydrolysis product HCl is acutely toxic for fish (pH-dependent).
Short-term toxicity to aquatic invertebrates
No data on the toxicity of stearoyl chloride and its hydrolysis product stearic acid are available.There is one study with sodium oleate (CAS 143 -19 -1) available, which can be used for a read-across approach. The 24 -h EC50 was determined to be 4.2 mg/L (Huber, 1991, in HERA, 2003).
The hydrolysis product hydrochloric acid (HCl) was tested in a semi-static acute toxicity test according to OECD 202 with Daphnia magna. The 48-h EC50 was 0.492 mg/L (acid equivalent to pH 5.3; OECD 2002). Hydrochloric acid is acutely very toxic to aquatic invertebrates.
Toxicity to aquatic algae and cyanobacteria
No data on the toxicity of stearoyl chloride are available. However, since the test substance rapidly hydrolyses in water, algae are mainly exposed to the hydrolysis product stearic acid.
The toxicity of stearic acid to algae was assessed via a study with the green alga Pseudokirchneriella subcapitata (Kamaya et al., 2003). Solvent (DMSO) was used to achieve the desired test concentrations. The 72 -h EC50 (cell number) of 11.72 mg/L indicates that stearic acid is acutely harmful to aquatic algae. The determined EC50 lies clearly above the water solubility limit (0.6 mg/L). Therefore it can be assumed that stearic acid is acutely harmful to aquatic algae, but no toxic effects will occur within the range of water solubility. Hydrochloric acid is acutely very toxic to aquatic algae.
The hydrolysis product hydrochloric acid (HCl) was tested in an algae growth inhibition test according to OECD 201 with Pseudokirchneriella subcapitata. The 72-h ErC50 was 0.492 mg/L (acid equivalent to pH 5.3), the 72 -h NOEC was 0.097 (acid equivalent to pH 6; OECD 2002).
Toxicity to microorganisms
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low amounts.
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