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EC number: 204-004-5
CAS number: 112-76-5
Groups of mice are exposed daily, for 3 consecutive days, to various
concentrations of the test chemical or to the relevant vehicle alone, on
the dorsum of both ears. On day 5 following the initiation of exposure,
mice are injected intravenously with [3H]thymidine and activity measured
as a function of isotope incorporation in draining auricular lymph nodes
(Kimber and Basketter, 1992). A stimulation index ≥ 3, together was
observed in all concentrations (5, 10, 25%). Therefore
Octadecanoylchlorid is regarded as sensitizing in the LLNA.
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