Registration Dossier

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: No GLP and no guideline was followed. No data on methodology.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1951

Materials and methods

Principles of method if other than guideline:
The dose was administred in drinking water. In this case appetite is judged on the basis of mililiters of water consumed.
GLP compliance:
not specified
Test type:
other: data not given
Limit test:
no

Test material

Constituent 1
Reference substance name:
79-36-7, 201-199-9, dichloroacetyl chloride
IUPAC Name:
79-36-7, 201-199-9, dichloroacetyl chloride
Constituent 2
Chemical structure
Reference substance name:
Dichloroacetyl chloride
EC Number:
201-199-9
EC Name:
Dichloroacetyl chloride
Cas Number:
79-36-7
Molecular formula:
C2HCl3O
IUPAC Name:
2,2-dichloroacetyl chloride
Details on test material:
- Name of test material (as cited in study report): Dichloroacetyl chloride

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Vehicle:
not specified
Control animals:
not specified
Details on study design:
- Duration of observation period following administration of Single -dose oral toxicity, 14 days

Results and discussion

Preliminary study:
LD50 2460mg/kg (1.83 - 3.23)
Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
2 460 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Single Dose Oral Toxicity for rats LD50= 2460mg/kg (1.83 - 3.23). Observations were realized during 14 days.
Executive summary:

The substance Single Dose Oral Toxicity for rats LD50 = 2460mg/kg (1.83 - 3.23). Observations were realized during 14 days.