Registration Dossier
Registration Dossier
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EC number: 201-199-9 | CAS number: 79-36-7
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: No GLP and no guideline was followed. The number of animals was not provided and few data on methodology was given.
Cross-reference
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 951
Materials and methods
- Principles of method if other than guideline:
- Penetration of rabbit Skin. DL50 measurement after 14 days.
- GLP compliance:
- not specified
- Limit test:
- no
Test material
- Reference substance name:
- Dichloroacetyl chloride
- EC Number:
- 201-199-9
- EC Name:
- Dichloroacetyl chloride
- Cas Number:
- 79-36-7
- Molecular formula:
- C2HCl3O
- IUPAC Name:
- 2,2-dichloroacetyl chloride
- Details on test material:
- - Name of test material (as cited in study report): Dichloroacetyl chloride
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- 14 days
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
- Statistics:
- 0.65 (0.53-0.81) ml/kg
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 0.65 mL/kg bw
Any other information on results incl. tables
LD 50 = 0.65 ml/kg (0.53 -0.81) after 14 days
Applicant's summary and conclusion
- Conclusions:
- The substance DL 50 in penetration of rabbit Skin was DL 50 = 0.65 ml/kg (0.53 -0.81). after 14 days
- Executive summary:
The substance DL 50 determined in penetration of rabbit Skin was DL 50 = 0.65 ml/kg (0.53 -0.81) after 14 days.
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