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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

The estimated bioconcentration factor (BCF) for clioquinol is 91 which does not exceed the bioconcentration threshold of 2000. Thus it is concluded that clioquinol is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.

Key value for chemical safety assessment

BCF (aquatic species):
91 dimensionless

Additional information

Bioaccumulation is the process by which the chemical concentration in an aquatic organism achieves a level that exceeds that in the water, as a result of chemical uptake through all possible routes of exposure.The relationship between bioaccumulation and bio-concentration is that, chemicals that have the potential to bioconcentrate also have the potential to bioaccumulate. Bioaccumulation is closely related to the Bioconcentration factor (BCF).

The estimated BCF of the key study was obtained to be 91.Supporting study also indicate the same BCF value. This low value of BCF of clioquinol indicates its non bioaccumulative nature as the BCF factor is less than the bio-concentration threshold of 2000.