Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-984-4 | CAS number: 130-26-7
Endpoint summary
Administrative data
Description of key information
Additional information
Biodegradation in water
The half life period ofclioquinolin water is 38 days and based on this value it can be concluded that the chemical is not persistent in water medium since the half life is less than the threshold of 60 days (to qualify the chemical as persistent). Also the diffusion percentage ofclioquinolin water medium is 11%. This coupled with the dilution of water shall result in ready biodegradabililty of the chemical.
The supporting study also shows the half life of clioquinol to be 900 hrs (37.5 days) indicating thet it is readily biodegradable
Media |
Half-Life |
Percent in |
Water |
38 |
11% |
Media |
Half life (hrs) |
Percent in Medium |
Emission (kg/hr)
|
Water |
900 |
10.8 |
1000 |
Biodegradation in water and sediment
Based on the Level III Fugacity Model, the half life period of the clioquinol was estimated. The half period ofclioquinolin water is 38 days (912 hrs) therefore it is considered that the substance will qualify as not persistent as the half life does not exceed the EPA criteria of 60 days. So, it can be confirmed that the substance is readily biodegradable in water medium where as in sediment the half life is 340 days (8160 hrs).
Based on this value, it can be inferred that the substance is persistent in sediment medium and is not readily biodegradable probably due to the anaerobic conditions existing in most sediments. However, it can be observed that clioquinol have very slightdiffusion in the sediment medium since it's percentage in the sediment medium is reported to be 3% and hence persistence in the sediment compartment is not likely to be critical.
Media |
Half-Life |
Percent in |
Water |
38 |
11% |
Sediment |
340 |
3 % |
Media |
Half life (hrs) |
Percent in Medium |
Emission (kg/hr)
|
Water |
900 |
10.8 |
1000 |
Sediment |
8100 |
3.38 |
0 |
Biodegradation in soil
The PBT Profiler & EPI Suite has estimated thatclioquinolis expected to be found predominantly in soil and its persistence estimate is based on its transformation in this medium. Its half-life in soil, 75 days (1800 hrs). This exceeds the threshold of >= 2 months (and <= 6 months). Therefore,clioquinolis estimated to be persistent in the soil environment.
PBT profiler estimate
Media |
Half-Life |
Percent in |
Soil |
75 |
86% |
Fugacity Model by EPI Suite estimation database
|
Mass Amount (percent) |
Half-Life (hr) |
Emissions (kg/hr) |
soil |
85.9 |
1.8e+003 |
1000 |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
