Registration Dossier
Registration Dossier
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EC number: 206-735-5 | CAS number: 371-40-4
Toxicity to terrestrial plants
Administrative data
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Reaxys ID : 742030
- Year:
- 2 011
- Bibliographic source:
- Reaxys by Elsevier Properties SA; Wang, Xiaodong; Sun, Cheng; Wang, Liansheng; Han, Shuokui; Environmental Toxicology and Chemistry; vol. 20; nb. 4; (2001); p. 913 - 916
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Germination test:- Semistatic exposure of 15 seeds germinated in solution of test compounf for 48 h in dark at 25 deg C and pH 6.75; The germination rate was calculated.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-fluoroaniline
- EC Number:
- 206-735-5
- EC Name:
- 4-fluoroaniline
- Cas Number:
- 371-40-4
- Molecular formula:
- C6H6FN
- IUPAC Name:
- 4-fluoroaniline
- Details on test material:
- - Name of test material: 4-fluoroaniline
- Molecular formula: C6H6FN
- Molecular weight: 111.12
- Substance type: Organic
- Physical state: Liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test substrate
- Vehicle:
- yes
- Details on preparation and application of test substrate:
- Kind of Dosing : solution of title compound in water was applied
Test organisms
- Species:
- Cucumis sativus
- Plant group:
- Dicotyledonae (dicots)
Study design
- Test type:
- seed germination/root elongation toxicity test
- Study type:
- laboratory study
- Substrate type:
- other: solution of title compound
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 25 deg C;
- pH:
- 6.75
- Details on test conditions:
- 15 seeds were germinated in solution of title compound for 48 h by semistatic exposure in dark at 25 deg C and pH 6.75
Control used: without test compound - Nominal and measured concentrations:
- 6 concentrations from no effect to 100 percent inhibition concentrations were used
Results and discussion
Effect concentrations
- Species:
- Cucumis sativus
- Duration:
- 48 h
- Dose descriptor:
- other: GC50
- Effect conc.:
- 519 other: mg/l
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- dissolved
- Basis for effect:
- germination
- Remarks on result:
- other: log 1/GC50 = 2.33
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The GC50 (inhibited germination rate by 50 percent) value of 4-fluoroaniline to Cucumis sativus during a 48 hr exposure is 519 mg/L.
- Executive summary:
The GC50 (inhibited germination rate by 50 percent) value of 4-fluoroaniline to Cucumis sativus during a 48 hr exposure is 519 mg/L.
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