Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
adult fish: sub(lethal) effects
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Log term fish toxicity by ECOSAR Version 1.10
Author:
ECOSAR Version 1.10
Year:
2012
Bibliographic source:
ECOSAR v1.1 Class-specific Estimations, Environmental Protection Agency (EPA) office of Chemical Safety and Pollution Prevention

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modeling database
Principles of method if other than guideline:
ECOSAR v1.1
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-fluoroaniline
EC Number:
206-735-5
EC Name:
4-fluoroaniline
Cas Number:
371-40-4
Molecular formula:
C6H6FN
IUPAC Name:
4-fluoroaniline
Details on test material:
- Name of test material: 4-fluoroaniline
- Molecular formula: C6H6FN
- Molecular weight: 111.12
- Substance type: Organic
- Physical state: Liquid

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
other: Fish

Study design

Test type:
not specified
Water media type:
not specified
Total exposure duration:
14 d

Results and discussion

Effect concentrations
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
71.994 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Conclusions:
The LC50 value of 4-fluoroaniline to Fish during a 14 day exposure is estimated to be 71.994 mg/L
Executive summary:

The LC50 value of 4-fluoroaniline to Fish during a 14 day exposure is estimated to be 71.994 mg/L