Registration Dossier
Registration Dossier
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EC number: 206-735-5 | CAS number: 371-40-4
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Dose doc.no. : F60
- Author:
- RSC Publishing
- Year:
- 2 011
- Bibliographic source:
- Dictionary of Substances and their effects (DOSE);Schultz, T. W. et al Bull. Environ. Contam. Toxicol. 1989, 43(4), 564-569.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is from DOSE Handbook
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-fluoroaniline
- EC Number:
- 206-735-5
- EC Name:
- 4-fluoroaniline
- Cas Number:
- 371-40-4
- Molecular formula:
- C6H6FN
- IUPAC Name:
- 4-fluoroaniline
- Details on test material:
- - Name of test material: 4-fluoroaniline
- Molecular formula: C6H6FN
- Molecular weight: 111.12
- Substance type: Organic
- Physical state: Liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Tetrahymena pyriformis
Study design
- Test type:
- not specified
- Water media type:
- not specified
- Total exposure duration:
- 48 h
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- IC50
- Effect conc.:
- 8 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The IC50 value of 4-fluoroaniline to Tetrahymena pyriformis during a 48hr exposure is 8 mg/L
- Executive summary:
The IC50 value of 4-fluoroaniline to Tetrahymena pyriformis during a 48hr exposure is 8 mg/L
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