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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

The concentration of the test substance in fish ranged from 0.37 to 1.08 µg/g (w/w) and the bioconcentration (BCF) was 2 to 5. On the basis of the BCF obtained, it is concluded that the bioaccumulation potential of the test substance in fish is low under the test condition.

Key value for chemical safety assessment

BCF (aquatic species):
5 dimensionless

Additional information

"Should read: BCF= 2 - 5"

As the test substance has a very low water solubility HCO-30 was used as solubilizer in the test system. If possible no solubilizer

should be applied to the test system. But as the results for the BCF are very small and the usage of a solubilizer is increasing the

concentration of the test substance in the test system, the present result can be used as a worst case displaying a very low

bioaccumulation potential for the substance under environmentally relevant conditions.

This endpoint was covered by read-across of a study of 1,4-bis[(2-ethyl-6-methylphenyl)amino]anthraquinone. This read-across is justified as both substances have very similar chemical structures, the main physicochemical parameters (vapour pressure, water solubility and dissociation constant) are in the same range and further all available toxicological studies for both substances revealed the same results. Therefore a read-across for other physicochemical, ecotoxicological or toxicological endpoints seems to be justified. More details about the read-across justification are displayed in a detailed document attached to the Annex of the CSR.