Registration Dossier

Administrative data

First-aid measures

Inhalation Remove from danger zone. Obtain immediate medical assistance.
Skin Contact Remove contaminated clothing. Rinse contaminated skin immediately with plenty of water and soap and seek medical advice.
Eye Contact Immediately rinse eyes thoroughly with running water as long as possible (approx. 15 min).
Take injured quickly to factory medical center or call an ambulance (code word: eye accident).
Ingestion Do not induce vomiting. In case of consciousness wash mouth with water and let drink some of water. Seek medical advice. Keep p atient at rest.

Fire-fighting measures

Suitable Extinguishing Media Alcohol resistent foam Dry sand carbon dioxide (CO2)
Unsuitable Extinguishing Media Water Fire-extinguishing powder N.A.
Protective equipment for firefighters Wear self-contained breathing apparatus and fire protective suite.

Accidental release measures

Personal precautions Avoid contact with the skin and the eyes. Avoid breathing hazardous vapors/dusts. Wear personal protective equipm ent. Keep away unprotected persons.
Environmental precautions Suppress gases/vapours/mists with water spray jet. Do not release on the soil or into drains.
Methods for cleaning Wash away remains with plenty of water. Transfer large quantities into a container, rinse the rest with plenty of water.
Accidental Release Remove all sources of ignition.
For personal protection see SDS chapter 8; for disposal considerations see SDS chapter 13

Handling and storage

Storage and Handling Precautions Open handling without suitable personal protective equipment must be avoided. Keep container tightly closed in a dry, cool and well-ventilated place.
For industrial hygiene measures see SDS chapter 8
Conditions of storage Protect against heat
Do not store together with Incompatible substances.
Technical measures/ Precautions Handle product only in closed system or provide appropriate exhaust ventilation at machinery.
Preventive Precautions (fire/explosion) Observe the usual precautionary measures required for mixtures containing organic solvents. Keep away from op en flames, hot surfaces and sources of ignition.

Transport information

Land transport (ADR/RID)

UN number:
3175
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Class:
4.1 / F1
Packaging group:
II
Labels:
4.1
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Remarksopen allclose all

Marine transport (IMDG)

UN number:
3175
Proper shipping name and description:
Solids containing flammable liquid, n.o.s. ( Methanol)
Class:
4.1
Packaging group:
II
Labels:
4.1
Remarks
LQ: 1 Kg

Air transport ICAO/IATA

UN number:
3175
Proper shipping name and description:
Solids containing flammable liquid, n.o.s. ( Methanol)
Class:
4.1
Packaging group:
II
Labels:
4.1
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Exposure controls / personal protection

List type
Novartis internal Benchmark Guidance Value: 0.1 mg/m3

Contains:
METHANOL
List type mg/m3 ppm
STEL-Spain (Short Term Exposure Limit) 0 0 /
Short term exposure limit EC 0 0 Poisoning by cutaneous absorption possible.
WEL-United Kingdom (15 minute TWA) 333 250 Poisoning by cutaneous absorption possible.
STEL Switzerland (Short term exposure limit) 1040 800 Maximum exposure: 4X15 min/shift.
STEL-Ireland (Short Term Exposure Limit) 310 250 Poisoning by cutaneous absorption possible.
STEL (ACGIH USA) Short term exposure limit 0 250 Poisoning by cutaneous absorption possible.
TLV-Values Austria 260 200 Poisoning by cutaneous absorption possible.
OEL-Spain (TLV) 266 200 /
EC-Exposure Limits 260 200 Poisoning by cutaneous absorption possible.
TLV-SUVA Switzerland 260 200 Does not cause harm to the unborn child, if air TLVs are res pected.
TLV- Germany (TRGS 900, Limit Values in the Ambient
Air at the Workplace) 270 200 Does not cause harm to the unborn child, if air TLVs are res pected. Poisoning by cutaneous absorption possible.
OEL-Ireland (TLV) 260 200 Poisoning by cutaneous absorption possible.
TLV-ACGIH USA 0 200 Poisoning by cutaneous absorption possible.
WEL-United Kingdom (8 hour TWA) 266 200 Poisoning by cutaneous absorption possible.
Odour threshold 4.5 /

Industrial Hygiene The personal protective measure may be adapted appropriately when working in closed systems or under laboratory condi tions.
Regular cleaning of equipment, work area and clothing.
Open handling at operator intervention points with local exhaust ventilation (e.g. downflow booths).
Internal working procedures available to personnel covering personal hygiene, standard cleaning, waste disposal and main tenance.
Personnel instructed and trained, regular refresher training established.
Double wardrobe must be available.
Open Handling Respiration : Full face mask (EN136)
Filter : ABEK-P3 (EN141)
Eye : Yes, by face mask
Hand : Normal length chemical-mechanical resistant gloves (EN374/EN388)
Glove Material : butylrubber
Breakthrough time: 240 min
Thickness: 0.5 mm
Additional protection : working clothes (EN 340)
chemical-resistant apron (EN467) and boots (EN345 S5)
These values are derived from experiments, literature and information from the glove manufacturer.
They can also be derived from similar materials. In daily work please be aware that the using time depends on several factors and can be shorter than the oficially tested permeation time.

Stability and reactivity

Conditions to avoid Keep away from open flames, hot surfaces and sources of ignition.
Dangerous Combustion Products carbon oxides
nitrogen oxides
hydrogen chloride

Disposal considerations

Disposal Requirements Incineration in an approved, controlled furnace with combustion gas scrubbing and emission gas control.
Container Disposal Empty containers can be disposed or re-used after cleaning, when in compliance with the environmental regulations ( Duty of Care).