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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
03 Sep. 2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
no
Type of method:
flask method
Remarks:
slow-stir modification

Test material

Constituent 1
Chemical structure
Reference substance name:
2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]propane-1,3-diol
EC Number:
923-654-7
Cas Number:
172529-94-1
Molecular formula:
C10H14N5O2Cl
IUPAC Name:
2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]propane-1,3-diol

Results and discussion

Water solubility
Water solubility:
25.5 g/L
Temp.:
20 °C
pH:
8

Any other information on results incl. tables

Flask 1: weighted sample 8.98 g/ 70 mL, pH 7.9, results of analysis: 527 / 532 / 520 mg/L

Flask 2: weighted sample 8.40 g/ 70 mL, pH 8.0, results of analysis: 519 / 523 / 514 mg/L

Flask 3: weighted sample 7.53 g/ 70 mL, pH 8.0, results of analysis: 484 / 482 / 496 mg/L

Mean value of all results is 511 mg/L.

The dilution ratio is 1:50.

Applicant's summary and conclusion